People in the Kohen Group

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Amnon Kohen

Dr. Amnon Kohen is an Associate Professor of Chemistry and of Molecular and Cellular Biology. Amnon was born in a kibbutz in northern Israel. He served for six year in the Israeli navy. He received his B.Sc. degree in Chemistry in 1989 from the Hebrew University in Jerusalem and D.Sc. 1994, Technion-Israel Institute of Technology. After that he was a postdoctorial fellow with Prof. Judith Klinman at the University of California at Berkeley. In 1999, he moved to the University of Iowa. His main interest is bioorganic chemistry and enjoys studying the mechanisms by which enzymes activate C-H bonds and N2 triple bonds. His research focuses on the relationship between enzyme structure, dynamics, and catalytic activity. He is also pursuing medical and technological applications of biological catalysts. amnon-kohen@uiowa.edu

 

Anatoly Chernyshev

Dr. Anatoly Chernyshev is a postdoctoral researcher studying nitrogenase, the first enzyme in a pathway of microbial nitrogen assimilation. He was born in Saratov, Russia, received his PhD from Saratov State University and eventually joined the Kohen group in September 2003. This specimen of H. sapiens describes himself as extremely humble and shy, so that general patterns of his social behavior are still scarcely known. Those few things found to the date about Anatoly are sketched at his website or one may get in touch with him via E-mail at a_chernyshev@yahoo.com.

Todd Flieschmann

Todd is a graduate student that joined our group in 2004 after finishing a B.S. in Chemistry and Agronomy at Northwest Missouri State University. Todd's current project centers around a newly discovered enzyme denoted Flavin Dependant Thymidylate Synthase. Recently, he has been working on protein expression and purification as well as enzyme mechanism studies. His hobbies include hunting, working on his house and playing with his son. .

Jigar Bandaria

Jigar has joined the group in January of 2004. jigar-bandaria@uiowa.edu

Atsushi Yahashiri

Atsushi Yahashiri was born in Tokyo, Japan. He received His MS degree from Biochemistry Department at UI 2004 and eventually joined the Kohen group in January 2005. Atsushi is currently studying the mechanism of a non-chromosomal DHFR (R67) as potential antibiotic drug for resistance strains of bacteria. He also enjoys the life in Iowa City with his wife and two kids. His hobbies are swimming, mowing lawn, planting fruits and vegetables, going to farmers market (buying), cooking, making good coffee, expressing ADH in vivo, bothering PI with questions, purifying enzymes, blogging, camping, and canoeing with Bryce Plapp (biannual).

yahashiri@hotmail.com

Arun Sen

Arundhuti Sen joined the Kohen group in 2005, after graduating from Knox College in Galesburg, IL. Arun is working on DHFR kinetics, following closely in the footsteps of Lin Wang. She likes to start every day with a loud 'Vive la resistance!' and a short prayer to the gods of the steady-state.

Vanja Stojkovic

Vanja is a graduate student that joined the Kohen group in Nov 2006.

Vishal Sharma

Hey, this is Vishal, I did my previous studies at University of Delhi, INDIA. I joined the group in Dec 2006. My interest is to study reaction mechanisms and I aspire to unfold the mysterious steps in enzymatic reactions. In addition to that I like Indian music and I am looking forward to form a music band after graduation. Wish me luck for both of my interests.

Zhen Wang

Born in a small town of Shandong Province, I'm a typical North Chinese girl, who is easy-going and laughs a lot. At the age of 6, I decided to be a life scientist, who will invent some medicine that my parents could take and live forever... As I growed up, I realized it was impossible. However, I still want to be a life scientist to solve some serious problems in our world. After graduation from Nanjing University in 2006, I came to United States. I believe the 5 years Ph.D. study here will help me to achieve my life legend. My favorite quote is "There are three best things in life--Eating, Sleeping, and Science" by Zhen Wang. *^_^*

Daniel Roston

Daniel grew up in the suburbs north of Chicago and graduated from Hamilton College in Clinton, NY with a chemistry degree in 2007. As an undergrad he worked in labs studying nanotechnology, organic natural products, and infectious diseases. Daniel joined the Kohen group in the fall of 2007 and is measuring kinetic isotope effects in the reaction catalyzed by alcohol dehydrogenase. He is very interested in the extent to which quantum mechanics invalidate classical transition state theory. When he is not in the lab, Daniel likes to play rugby and read about the crazy ideas physicists are cooking up these days. When he grows up, Daniel wants to be an astronaut. For real.

Eric Koehn

 

 

Group Pictures from Conferences and Treats

Get-together in the new office when Zhen passed her Comps

Winter Gathering 2007

The group in MECC conference in Chicago Oct. 2006

Lin Wang's Goodbye Party 2

Lin Wang's Goodbye Party 1

MECC Conference Chicago 2006

At the lake 2006

At the lake 2006

GRC 2006

GRC 2006

Group 2005

Dec 2004

Fun at MECC

Posters

Lunch in MECC 2001

 

Former Members


Lin Wang

Lin WangLin, joined this group in 2002 and graduated with a PhD in Dec 2006. Currently he is writing a few papers and prepare for his Postdoctoral position.. Before that he spent four years sleeping through classes at Ocean University of Qingdao, P.R.C. and another three years at Zhejiang University, P.R.C.. Lin finds here, in this university, he cannot get enough time for interesting extracurricular activities, which is due to the fact that we have a highly motivated group! His current research focuses on the C-H bond activation project. His main hobbies includes algebra, statistics and software. lin-wang@uiowa.edu

Baoyu Hong

Baoyu HongBaoyu is a graduate student from China and joined this group in summer of 2003. She got B.E. degree in Packaging Engineering in 1999 and M. S. degree in Polymer Science in 2002 from Jilin Unversity, China. Then the same year she came to the Unversity of Iowa. Her current research project is classical TS. At spare time, she loves movies, photography, traveling and celtic music.

Majd Haddad

Majd was born in Brest, France original from Lattakia, Syria. He lived in different countries and decided to continue his college education in the United States. Currently, he is a junior majoring in Biochemistry and an Iowa Biosciences Advantage scholar. He intends to attend graduate school and earn a doctoral degree so that he can continue training and conduct research in enzymology. This summer he was involved with Scott in s

Melissa Hall

Melissa was a graduate student Jan-Dec 2006.

 

Aaron Mason

Aaron Mason completed his undergraduate work at Cornell College (2005) with a double major in Chemistry and Biochemistry. His was in the Biosciences Program at the University of Iowa and was rotating through the Kohen Lab. Aaron was studying a flavin dependent thymidylate synthase.

Kelli Markham

Dr.Kelli Markham received her Ph.D. in Chemistry in 2004 and was the first to graduate with Ph.D. from the Kohen Group. Kelli's last position in iowa was a visiting Assistant Professor and a Postdoctoral Scholar in the Kohen Group. She receivedher B.A. degree in Chemistry from Lake Forrest College in Illinois in 1998. The summer after her graduation she completed an internship at Abbott Labs in IL. After this, she worked on a project for the DOE, testing for radioactivity (U-235, Tc-99 etc.) in soil and water samples. Kelli entered this university in the Fall of 1999, and since then has worked out the synthesis of key radio-labeled nucleotides for enzyme kinetic studies and completed preliminary KIE studies with DHFR. Currently, Kelli is investigating the chemistry of several enzymes, including:glutamate dehydrogenase and thermophilic dihydrofolate reductase (DHFR). Kelli's hobbies include home remodelling projects with her husband, Dale, and roughhousing with her 150 lb Great Dane, Apollo.

Kellis is now in Washington DC working for NRC. kxm4@nrc.gov

 

Nitish Agrawal

Dr. Nitish Agrawal earned his Ph.D in Chemistry in July 2005. He is originally from India. He joined this group in Fall 2001. Nitish loves America. Nitish was born in Aligarh, Uttar Pradesh, in India. He was schooled at Delhi Public School, Mathura Road, New Delhi, India. He received his B.Sc (Honors) degree in Chemistry in 1999 with distinction, and his M.Sc. (Chemistry), specialization in Organic Chemistry in 2001 with distinction from Hindu College, University of Delhi, India. Nitish has qualified National Eligibility Test (NET) in India, which entitles him to join any Public College/University as Lecturer/Research Investigator in India. At UI, he has been a prime researcher on four projects: enzymatic synthesis of labeled nicotinamide cofactor; chemoenzymatic synthesis of labeled derivatives of folic acid; mechanistic studies of E.coli thymidylate synthase (TS); and mechanistic studies of flavin-dependent TS (FDTS). Nitish is currently studying FDTS, which shares no sequence or structure homology with common TS. This is a very high impact type of research since FDTS catalysis is the only path that many biological warfare agents use to synthesize DNA. He has also recently won a prestigious Ph.D fellowship from the Center for Biocatalysis and Bioprocessing (CBB). His general interests and activites include reading and writing articles on science education, traveling, listening to music and playing guitar.

Nitish is now working with GE Global Research in Albany, New York .

Scott Tharp

Scott is a talented undergraduate who joined the group in the Summer of 2003. One can often hear Scott talking to himself as he does injection after injection on the HPLC. We consider this normal behavior so please do not feel frightened. He is now a DDC student.

Pierre Charly Point Du Jour

Pierre Charly Point Du Jour was born in Cayes, Haiti. Pierre lives in New York City with his parents whereas he attends Florida Memorial University pursuing his undergraduate studies in biology and chemistry. Planning to attend the Medical Scientist Training Program (MSTP) at the University of Iowa, through the AGEP Program in summer 2004, Pierre worked with the Eyeman Group on ÒSurface Deposition of Single-Site Redox Reactant.Ó This summer 2005, Pierre has joined the Kohen Group while working on ÒMechanistic Studies of Hydride Transfer Catalyzed by E. coli Thymidylate Synthase W80M Mutant.Ó Pierre has not only done science, but he is also a poet/playwright and some of his works can read on his website (www.jeanpointdujour.org) or you may contact him via email at pcpdj@yahoo.com

Wilmarie Santana

Wilmarie Santana is a sophomore student from University of Puerto Rico-Bayamon working inthe Kohen group on a SROP fellowship.

 

Cornelia Mihai

Cornelia is an Assistant Professor of Organic Chemistry at Northwetern Okalhoma State University. She was born in Bucharest, Romania. She received her B.S. degree in Chemical Engineering from Polytechnic Institute of Bucharest. After that, she was working as a chemical engineer and then as a Research Scientist at the Food Chemistry Institute and at the Institute of Oncology in Bucharest. In 1994 she started her graduate studies in United States and she received her M.S. degree in Chemistry in 1996 and her Ph.D. degree in Medicinal Chemistry in 2001 from University of Illinois at Chicago. After that she was working as Research Associate at Albany Molecular Research, Inc. and as Research Scientist at Integrated DNA Technologies in Coralville, Iowa. In 2002, she took the position as a Postdoctoral Associate in the Kohen group. Currently, she is working on expressing and purifying the enzymes needed for kinetic and structural studies. Her research interests are Bioorganic Chemistry, Medicinal Chemistry and Synthetic Enzymology and she enjoys studying the mechanism, structure and dynamics of the enzymes that are targets for therapeutic drugs. new URL: http://www.nwosu.edu/science/.

Steve Sikorski

Steve was a post-doc in the Kohen group who received his Bachelor Degree at Bradley University in Peoria and his PhD here at the University of Iowa with Dr. Dan Quinn, working on acetylcholinesterase and low-barrier hydrogen bonds. He has worked at both the U.S. Department of Agriculture and Walter Reed Army Institute. Steve also became a lecturer here at the University of Iowa teaching Organic Chemistry laboratory and Organic and General Chemistry courses, for one year before returning to research. While with the Kohen group Steve studied temperature dependencies on KIEÕs for dihydrofolate reductase. Steve is now holds an industrial position for a company in Springfield, MO.

Amandeep Sra

Amandeep Kaur Sra was born in Mumbai (Bombay), India. She received her Bachelor of Science and Master of Science degrees in chemistry from the University of Mumbai. For her Ph.D. in Chemistry at the University of Mumbai, she worked on the design and study of molecular magnetic materials with Dr. J.V. Yakhmi, B.A.R.C., India and with Prof. O. Kahn, ICMCB, France. She received the Young Scientist award '99 in Physical Chemistry at the International Symposium of the Indian Chemical Society. Amandeep worked on establishing the vacuum apparatus enabling the study of nitrogenase. After many laborious hours she managed to measure competitive KIEs for this system. Aman has ventured off for her second post-doc at Texas A&M.

Carla Asbury

Carla was an undergraduate in the group, working on improving HPLC separations for KIE studies.

 

 

 

 

Lena Rydberg

Lena was an undergraduate in our lab, from the Department of Biochemistry here at the University of Iowa. Lena worked in our lab for a summer doing synthesis of deuterated substrates.

 

 

 

Jocelyn McCracken

Jocelyn McCracken graduated from Fairfield High School, Fairfield, Iowa in 1996 and majored in chemistry and english while attending Central College in Pella, IA. Jocelyn graduated in the summer of 2002 with a Master's degree and is currently living in the suburbs of Chicago with her husband, Tim, as she searches for employment. We wish her the best of luck and are waiting for a phone call when she makes her first million dollars.

 

Malia Moore

Malia Moore graduated from Hope High School (in Hope, Kansas) in 1996 and received her B.S. in chemistry in 2000 from University of Rochester in Rochester, NY. Malia graduated the summer of 2002 from this group with a Master's and is curently in medical school at KU. We wish her the best of luck in all of her future endeavors.

 

 

 

Jeff Smith

Jeff is an undergraduate student from Burlington, Iowa. He was responsible (among other things) for the web page, and installing any and every new fancy piece of equipment. He graduated in December 2000 with a B.S. degree in Chemistry with Honors. Currently, we have no news as to his whereabouts. Last we heard he was working as a tech for microscopists, here at the University of Iowa where he was treasured as a valuable asset to their laboratory. If you or anyone you know has any information about the location of Jeff Smith, please call America's Most Wanted immediately and then let us know. Do not attempt any communication with this person, you can tell from his picture just the types of evil deeds he is capable of.

 

 


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